Trimethylamine N-Oxide (TMAO) Inducing Endothelial Injury: UPLC-MS/MS-Based Quantification and the Activation of Cathepsin B-Mediated NLRP3 Inflammasome
TMAO is a new risk biomarker for cardiovascular disease. With trimethylammonium as its main chemical skeleton, TMAO is structurally similar to many endogenous metabolites, such as acetylcholine, carnitine, phosphorylcholine, etc. The mechanism of TMAO on the pathological process of CVD is still uncl...
Main Authors: | Dongyu Lei, Wenbo Yu, Yi Liu, Yujie Jiang, Xiaohui Li, Jing Lv, Ying Li |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/28/9/3817 |
Similar Items
-
SPE–UPLC–MS/MS for Determination of 36 Monomers of Alkylphenol Ethoxylates in Tea
by: Qin Lin, et al.
Published: (2023-04-01) -
Determination of Aflatoxins in Grains by QuEChERS-UPLC-MS/MS
by: WU Qin-yan, et al.
Published: (2024-03-01) -
Validation of UPLC-MS/MS Method for Determination of Urinary Lactulose/Mannitol
by: Jacopo Gervasoni, et al.
Published: (2018-10-01) -
Quantitative Analysis of Eight Compounds in Traditional Korean Medicine, Gongjindan Using HPLC, UPLC–MS/MS, and GC–MS/MS Systems
by: Chang-Seob Seo, et al.
Published: (2023-03-01) -
Determination of oleandrin and adynerin in rat plasma by UPLC–MS/MS and their pharmacokinetic study
by: Meiling Zhang, et al.
Published: (2022-12-01)