Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness

Abstract Patients with severe alcoholic hepatitis (SAH) not responding to glucocorticoid therapy have higher mortality, though they do not differ in their baseline clinical characteristics and prognostic scores from those who respond to therapy. We hypothesized that the baseline hepatic gene express...

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Bibliographic Details
Main Authors: Shvetank Sharma, Jaswinder S. Maras, Sukanta Das, Shabir Hussain, Ashwani K. Mishra, Saggere M. Shasthry, Chhagan B. Sharma, Emmanuel Weiss, Laure Elkrief, Pierre-Emmanuel Rautou, Hélène Gilgenkrantz, Sophie Lotersztajn, Valérie Paradis, Pierre de la Grange, Christophe Junot, Richard Moreau, Shiv K. Sarin
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07161-4