The Impact of Hidden Structure on Aggregate Disassembly by Molecular Chaperones

Protein aggregation, or the uncontrolled self-assembly of partially folded proteins, is an ever-present danger for living organisms. Unimpeded, protein aggregation can result in severe cellular dysfunction and disease. A group of proteins known as molecular chaperones is responsible for dismantling...

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Bibliographic Details
Main Authors: Daniel Shoup, Andrew Roth, Jason Puchalla, Hays S. Rye
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.915307/full