<i>N</i>-Acylated and <i>N</i>-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E<sub>2</sub>

<i>N</i>-Acylated and <i>N</i>-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E<sub>2</sub>

The quest for novel agents to regulate the generation of prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) is of high importance because this eicosanoid is a key player in inflammatory diseases. We synthesized a series of <i>N</i>-acylated and <i>N</i>-alk...

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Bibliographic Details
Main Authors: Maria A. Theodoropoulou, Anastasia Psarra, Martin Erhardt, Aikaterini Nikolaou, Anna-Dimitra D. Gerogiannopoulou, Dimitra Hadjipavlou-Litina, Daiki Hayashi, Edward A. Dennis, Andrea Huwiler, George Kokotos
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
<i>N</i>-acylated 2-aminobenzothiazoles
<i>N</i>-alkylated 2-aminobenzothiazoles
anti-inflammatory agents
mesangial cells
prostaglandin E<sub>2</sub>
Online Access:https://www.mdpi.com/2218-273X/12/2/267

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https://www.mdpi.com/2218-273X/12/2/267

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