Increased Internal Porosity and Surface Area of Hydroxyapatite Accelerates Healing and Compensates for Low Bone Marrow Mesenchymal Stem Cell Concentrations in Critically-Sized Bone Defects

Increased Internal Porosity and Surface Area of Hydroxyapatite Accelerates Healing and Compensates for Low Bone Marrow Mesenchymal Stem Cell Concentrations in Critically-Sized Bone Defects

For clinical treatment of skeletal defects, osteoinductive scaffolds must have the ability to conform to the unique geometry of the injury site without sacrificing biologically favorable properties, including porosity. This investigation seeks to combine the osteoinductive properties of porous hydro...

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Bibliographic Details
Main Authors: Eileen R. Dawson, Richard K. Suzuki, Melissa A. Samano, Matthew B. Murphy
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Applied Sciences
Subjects:
hydroxyapatite
biomaterial porosity
mesenchymal stem cell
bone marrow aspirate
bone regeneration
Online Access:http://www.mdpi.com/2076-3417/8/8/1366

Internet

http://www.mdpi.com/2076-3417/8/8/1366

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