PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway
Abstract Background This article reports the effects of proenkephalin (PENK) on osteosarcoma (OS) cell migration. Methods A Gene Expression Omnibus (GEO) dataset was used to identify differentially expressed genes (DEGs) in OS tumor samples and normal human osteoblasts. Tumor tissue and adjacent nor...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13018-020-01679-6 |