Decarboxylative oxidation-enabled consecutive C-C bond cleavage

The selective cleavage of inert C(sp3)-C(sp3) bonds and their subsequent functionalization is an important goal in synthetic organic chemistry. Here, the authors developed consecutive C–C bond cleavage from stable trisubstituted acids via photocatalysis and copper catalysis.

Bibliographic Details
Main Authors: Ruining Li, Ya Dong, Shah Nawaz Khan, Muhammad Kashif Zaman, Junliang Zhou, Pannan Miao, Lifu Hu, Zhankui Sun
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34829-x