Decarboxylative oxidation-enabled consecutive C-C bond cleavage
The selective cleavage of inert C(sp3)-C(sp3) bonds and their subsequent functionalization is an important goal in synthetic organic chemistry. Here, the authors developed consecutive C–C bond cleavage from stable trisubstituted acids via photocatalysis and copper catalysis.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34829-x |
| _version_ | 1798016827585986560 |
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| author | Ruining Li Ya Dong Shah Nawaz Khan Muhammad Kashif Zaman Junliang Zhou Pannan Miao Lifu Hu Zhankui Sun |
| author_facet | Ruining Li Ya Dong Shah Nawaz Khan Muhammad Kashif Zaman Junliang Zhou Pannan Miao Lifu Hu Zhankui Sun |
| author_sort | Ruining Li |
| collection | DOAJ |
| description | The selective cleavage of inert C(sp3)-C(sp3) bonds and their subsequent functionalization is an important goal in synthetic organic chemistry. Here, the authors developed consecutive C–C bond cleavage from stable trisubstituted acids via photocatalysis and copper catalysis. |
| first_indexed | 2024-04-11T15:56:50Z |
| format | Article |
| id | doaj.art-72f5f8a437a24b28820c9eae0ab7b77e |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T15:56:50Z |
| publishDate | 2022-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-72f5f8a437a24b28820c9eae0ab7b77e2022-12-22T04:15:08ZengNature PortfolioNature Communications2041-17232022-11-0113111210.1038/s41467-022-34829-xDecarboxylative oxidation-enabled consecutive C-C bond cleavageRuining Li0Ya Dong1Shah Nawaz Khan2Muhammad Kashif Zaman3Junliang Zhou4Pannan Miao5Lifu Hu6Zhankui Sun7Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Pharm-X Center, School of Pharmacy, Shanghai Jiao Tong UniversityThe selective cleavage of inert C(sp3)-C(sp3) bonds and their subsequent functionalization is an important goal in synthetic organic chemistry. Here, the authors developed consecutive C–C bond cleavage from stable trisubstituted acids via photocatalysis and copper catalysis.https://doi.org/10.1038/s41467-022-34829-x |
| spellingShingle | Ruining Li Ya Dong Shah Nawaz Khan Muhammad Kashif Zaman Junliang Zhou Pannan Miao Lifu Hu Zhankui Sun Decarboxylative oxidation-enabled consecutive C-C bond cleavage Nature Communications |
| title | Decarboxylative oxidation-enabled consecutive C-C bond cleavage |
| title_full | Decarboxylative oxidation-enabled consecutive C-C bond cleavage |
| title_fullStr | Decarboxylative oxidation-enabled consecutive C-C bond cleavage |
| title_full_unstemmed | Decarboxylative oxidation-enabled consecutive C-C bond cleavage |
| title_short | Decarboxylative oxidation-enabled consecutive C-C bond cleavage |
| title_sort | decarboxylative oxidation enabled consecutive c c bond cleavage |
| url | https://doi.org/10.1038/s41467-022-34829-x |
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