The structural dynamics of the flavivirus fusion peptide-membrane interaction.

The structural dynamics of the flavivirus fusion peptide-membrane interaction.

Membrane fusion is a crucial step in flavivirus infections and a potential target for antiviral strategies. Lipids and proteins play cooperative roles in the fusion process, which is triggered by the acidic pH inside the endosome. This acidic environment induces many changes in glycoprotein conforma...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ygara S Mendes, Nathalia S Alves, Theo L F Souza, Ivanildo P Sousa, M Lucia Bianconi, Rafael C Bernardi, Pedro G Pascutti, Jerson L Silva, Andre M O Gomes, Andréa C Oliveira
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3477123?pdf=render

Online

http://europepmc.org/articles/PMC3477123?pdf=render

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