The structural dynamics of the flavivirus fusion peptide-membrane interaction.

Membrane fusion is a crucial step in flavivirus infections and a potential target for antiviral strategies. Lipids and proteins play cooperative roles in the fusion process, which is triggered by the acidic pH inside the endosome. This acidic environment induces many changes in glycoprotein conforma...

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Main Authors: Ygara S Mendes, Nathalia S Alves, Theo L F Souza, Ivanildo P Sousa, M Lucia Bianconi, Rafael C Bernardi, Pedro G Pascutti, Jerson L Silva, Andre M O Gomes, Andréa C Oliveira
Format: Article
Jezik:English
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3477123?pdf=render