Antioxidant Quercetin 3-<i>O</i>-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization

Antioxidant Quercetin 3-<i>O</i>-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization

Plants are rich in secondary metabolites, which are often useful as a relevant source of nutraceuticals. Quercetin (QUE) is a flavonol aglycone able to bind Transthyretin (TTR), a plasma protein that under pathological conditions can lose its native structure leading to fibrils formation and amyloid...

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Bibliographic Details
Main Authors: Lidia Ciccone, Nicolò Tonali, Carole Fruchart-Gaillard, Lucia Barlettani, Armando Rossello, Alessandra Braca, Elisabetta Orlandini, Susanna Nencetti
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Crystals
Subjects:
transthyretin
TTR
quercetin 3-<i>O</i>-glycosylated derivatives
amyloidosis
antioxidant
plant bioactive metabolites
Online Access:https://www.mdpi.com/2073-4352/12/5/638

Internet

https://www.mdpi.com/2073-4352/12/5/638

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