Integrin-mediated electric axon guidance underlying optic nerve formation in the embryonic chick retina
Abstract Retinal ganglion cell (RGC) axons converge on the optic disc to form an optic nerve. However, the mechanism of RGC axon convergence remains elusive. In the embryonic retina, an electric field (EF) exists and this EF converges on the future optic disc. EFs have been demonstrated in vitro to...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-06-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-05056-x |