Branched‐Chain Amino Acids in Computed Tomography–Defined Adipose Depots and Coronary Artery Disease: A PROMISE Trial Biomarker Substudy

Branched‐Chain Amino Acids in Computed Tomography–Defined Adipose Depots and Coronary Artery Disease: A PROMISE Trial Biomarker Substudy

Background The interplay between branched‐chain amino acid (BCAA) metabolism, an important pathway in adiposity and cardiometabolic disease, and visceral adipose depots such as hepatic steatosis (HS) and epicardial adipose tissue is unknown. We leveraged the PROMISE clinical trial with centrally adj...

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Bibliographic Details
Main Authors: Elizabeth Zhao, Stephanie N. Giamberardino, Neha J. Pagidipati, Deepak Voora, Geoffrey S. Ginsburg, Udo Hoffmann, Júlia Karády, Maros Ferencik, Pamela S. Douglas, Borek Foldyna, Svati H. Shah
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
branched‐chain amino acids
coronary artery disease
coronary computed tomography angiography
epicardial adipose tissue
hepatic steatosis
Mendelian randomization analysis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.028410

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https://www.ahajournals.org/doi/10.1161/JAHA.122.028410

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