Chimeric Antigen Receptor (CAR)-T Cell Immunotherapy Against Thoracic Malignancies: Challenges and Opportunities

Chimeric Antigen Receptor (CAR)-T Cell Immunotherapy Against Thoracic Malignancies: Challenges and Opportunities

Different from surgery, chemical therapy, radio-therapy and target therapy, Chimeric antigen receptor-modified T (CAR-T) cells, a novel adoptive immunotherapy strategy, have been used successfully against both hematological tumors and solid tumors. Although several problems have reduced engineered C...

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Bibliographic Details
Main Authors: Long Chen, Fukun Chen, Huatao Niu, Jindan Li, Yongzhu Pu, Conghui Yang, Yue Wang, Rong Huang, Ke Li, Yujie Lei, Yunchao Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
thoracic malignancies
chimeric antigen receptor-modified T cells
immunotherapy
targeting specific antigens
solid tumor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.871661/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.871661/full

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