Mechanistic elucidation of freezing-induced surface decomposition of aluminum oxyhydroxide adjuvant

Mechanistic elucidation of freezing-induced surface decomposition of aluminum oxyhydroxide adjuvant

Summary: The freezing-induced aggregation of aluminum-based (Alum) adjuvants has been considered as the most important cause of reduced vaccine potency. However, the intrinsic properties that determine the functionality of Alum after freezing have not been elucidated. In this study, we used engineer...

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Bibliographic Details
Main Authors: Jiahuan Li, Ge Yu, Zhihui Liang, Min Li, Chen Chen, Xin Li, Yiyang Guo, Cheng Yang, Yang Liu, Caiqiao Zhang, Weiting Zhang, Jiaxu Liu, Xuehu Ma, Changying Xue, Bingbing Sun
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:iScience
Subjects:
Inorganic materials
Biotechnology
Materials science
Materials chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222007271

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http://www.sciencedirect.com/science/article/pii/S2589004222007271

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