Decreasing Compensatory Ability of Concentric Ventricular Hypertrophy in Aortic-Banded Rat Hearts

Decreasing Compensatory Ability of Concentric Ventricular Hypertrophy in Aortic-Banded Rat Hearts

The cardiac system compensates for variations in physiological and pathophysiological conditions through a dynamic remodeling at the organ, tissue, and intracellular levels in order to maintain function. However, on longer time scales following the onset of ventricular pressure overload, such remode...

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Bibliographic Details
Main Authors: Alexandre Lewalle, Sander Land, Eric Carruth, Lawrence R. Frank, Pablo Lamata, Jeffrey H. Omens, Andrew D. McCulloch, Steven A. Niederer, Nicolas P. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Physiology
Subjects:
ejection fraction
hypertrophy
cardiac compensation
aortic banding
left ventricle
computational modeling
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00037/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00037/full

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