Antiproliferative Evaluation of Novel 4-Imidazolidinone Derivatives as Anticancer Agent Which Triggers ROS-Dependent Apoptosis in Colorectal Cancer Cell

Antiproliferative Evaluation of Novel 4-Imidazolidinone Derivatives as Anticancer Agent Which Triggers ROS-Dependent Apoptosis in Colorectal Cancer Cell

Colorectal cancer (CRC) is one of the most common causes of cancer-related death worldwide, and more therapies are needed to treat CRC. To discover novel CRC chemotherapeutic molecules, we used a series of previously synthesized novel imidazolidin-4-one derivatives to study their anticancer role in...

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Bibliographic Details
Main Authors: Jiuhong Huang, Juanli Wang, Guiting Song, Chunsheng Hu, Zhigang Xu, Zhongzhu Chen, Chuan Xu, Donglin Yang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
4-imidazolidinone
colorectal cancer
apoptosis
ROS
JNK
Online Access:https://www.mdpi.com/1420-3049/27/24/8844

Internet

https://www.mdpi.com/1420-3049/27/24/8844

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