PreS1 Containing HBc VLPs for the Development of a Combined Therapeutic/Prophylactic Hepatitis B Vaccine

PreS1 Containing HBc VLPs for the Development of a Combined Therapeutic/Prophylactic Hepatitis B Vaccine

The available HBV vaccines based on the HBV surface protein are manufactured in yeasts and demonstrate excellent prophylactic but no therapeutic activity and are thus ineffective against chronic HBV infection. Five different HBV core proteins (HBc)—full length and C-terminally truncated—were used fo...

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Bibliographic Details
Main Authors: Andris Dishlers, Ivars Petrovskis, Dace Skrastina, Ieva Zarina, Ilva Lieknina, Juris Jansons, Inara Akopjana, Jelena Zakova, Velta Ose, Irina Sominskaya
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Microorganisms
Subjects:
HBV
HBc
virus like particles
immunogenicity
packaging
Online Access:https://www.mdpi.com/2076-2607/11/4/972

Internet

https://www.mdpi.com/2076-2607/11/4/972

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