Unraveling the enigma of B cells in diffuse large B-cell lymphoma: unveiling cancer stem cell-like B cell subpopulation at single-cell resolution

Unraveling the enigma of B cells in diffuse large B-cell lymphoma: unveiling cancer stem cell-like B cell subpopulation at single-cell resolution

BackgroundDiffuse large B-cell lymphoma (DLBCL) represents the most prevalent form of aggressive non-Hodgkin lymphoma. Despite receiving standard treatment, a subset of patients undergoes refractory or recurrent cases, wherein the involvement of cancer stem cells (CSCs) could be significant.MethodsW...

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Bibliographic Details
Main Authors: Fengling Liu, Jie Zheng, Gaohui Yang, Lin Pan, Yanni Xie, Siyu Chen, Jinwei Tuo, Jinxia Su, Xiuyi Ou, Rongrong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
diffuse large B cell lymphoma
cancer stem cell
single-cell RNA sequencing
bulk RNA sequencing
transcription factor
immune escape
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1310292/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1310292/full

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