DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells

DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells

Regulation of the epigenome during in vivo specification of brain stem cells is still poorly understood. Here, we report DNA methylome analyses of directly sampled cortical neural stem and progenitor cells (NS/PCs) at different development stages, as well as those of terminally differentiated cortic...

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Bibliographic Details
Main Authors: Tsukasa Sanosaka, Takuya Imamura, Nobuhiko Hamazaki, MuhChyi Chai, Katsuhide Igarashi, Maky Ideta-Otsuka, Fumihito Miura, Takashi Ito, Nobuyuki Fujii, Kazuho Ikeo, Kinichi Nakashima
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
epigenetics
DNA methylation
neural stem/progenitor cell
nuclear factor I
NFI
differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312287

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http://www.sciencedirect.com/science/article/pii/S2211124717312287

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