Vaginal microbial shifts are unaffected by oral pre-exposure prophylaxis in South African women

Abstract Vaginal microbiota have been shown to be a modifier of protection offered by topical tenofovir in preventing HIV infection in women, an effect not observed with oral tenofovir-based pre-exposure prophylaxis (PrEP). It remains unclear whether PrEP can influence the vaginal microbiota composi...

Full description

Bibliographic Details
Main Authors: Noluthando Mazibuko-Motau, Parveen Sobia, Jiawu Xu, Joseph Ahmed Elsherbini, James E. San, Lara Lewis, Andile Mtshali, Gugulethu Mzobe, Lungelo Ntuli, Salim S. Abdool Karim, Leila E. Mansoor, Quarraisha Abdool Karim, Douglas S. Kwon, Derseree Archary, Sinaye Ngcapu
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20486-z