WDR79 promotes aerobic glycolysis of pancreatic ductal adenocarcinoma (PDAC) by the suppression of SIRT4

Pancreatic cancer (PC) is an aggressive malignant disease. Pancreatic ductal adenocarcinoma (PDAC) is a main type of PDAC. The inhibition of aerobic glycolysis in PC cells is one of the approaches to treat PDAC. WD repeat protein 79 (WDR79) acts as a scaffold protein and is involved in several physi...

Full description

Bibliographic Details
Main Authors: Yin Wenke, Song Xiaoyan, Xiang Yue
Format: Article
Language:English
Published: De Gruyter 2023-01-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2022-0624