Contribution of KIR (killer immunoglobulin-like receptor) genes, HLA class I ligands, and KIR/HLA class I ligand combinations on the genetic predisposition to celiac disease and coexisting celiac disease and type 1 diabetes mellitus

Contribution of KIR (killer immunoglobulin-like receptor) genes, HLA class I ligands, and KIR/HLA class I ligand combinations on the genetic predisposition to celiac disease and coexisting celiac disease and type 1 diabetes mellitus

Backgound and aim: There are some common genetic features between celiac disease (CD) and diabetes mellitus type 1 (DM). However, the genetic risk factors have not been fully clarified for CD and the co-occurrence of CD and DM. KIR (killer immunoglobulin-like receptor) genes regulate the cytolitic a...

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Bibliographic Details
Main Authors: H. Haluk Akar, Turkan Patiroglu, Eylem Sevinc, Duran Aslan, Deniz Okdemir, Selim Kurtoglu
Format: Article
Language:English
Published: Aran Ediciones 2015-09-01
Series:Revista Espanola de Enfermedades Digestivas
Subjects:
Celiac disease
KIR genes
KIR ligands
KIR/KIR ligand combinations
Type 1 diabetes mellitus
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082015000900005&lng=en&tlng=en

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http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082015000900005&lng=en&tlng=en

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