A major role for Nrf2 transcription factors in cell transformation by KSHV encoded oncogenes

Kaposi’s sarcoma (KS) is the most common tumor in AIDS patients. The highly vascularized patient’s skin lesions are composed of cells derived from the endothelial tissue transformed by the KSHV virus. Heme oxygenase-1 (HO-1) is an enzyme upregulated by the Kaposi´s sarcoma-associated herpesvirus (KS...

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Bibliographic Details
Main Authors: Daiana Sapochnik, Ana R. Raimondi, Victoria Medina, Julian Naipauer, Enrique A. Mesri, Omar Coso
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.890825/full