Insights into Hepatitis B Virus DNA Integration-55 Years after Virus Discovery

Insights into Hepatitis B Virus DNA Integration-55 Years after Virus Discovery

Hepatitis B virus (HBV), which was discovered in 1965, is a threat to global public health. HBV infects human hepatocytes and leads to acute and chronic liver diseases, and there is no cure. In cells infected by HBV, viral DNA can be integrated into the cellular genome. HBV DNA integration is a comp...

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Bibliographic Details
Main Authors: Kaitao Zhao, Andrew Liu, Yuchen Xia
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:The Innovation
Subjects:
hepatitis B virus
integration
non-homologous end joining
insertional mutagenesis
hepatocellular carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2666675820300345

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http://www.sciencedirect.com/science/article/pii/S2666675820300345

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