Circular RNA-0007059 protects cell viability and reduces inflammation in a nephritis cell model by inhibiting microRNA-1278/SHP-1/STAT3 signaling

Abstract Background Increasing evidence has indicated that circular RNAs (circRNAs) play a role in various diseases. However, the influence of circRNAs in nephritis remains unknown. Methods Microarray analysis and RT-qPCR were used to detect the expression of circRNA. Type I IFN were administrated t...

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Bibliographic Details
Main Authors: Peng-Wei Guo, Hai-Ting Huang, Jing Ma, Yao Zuo, Dan Huang, Lin-Lin He, Zi-Ming Wan, Cheng Chen, Fa-Fen Yang, Yan-Wu You
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-021-00372-6