Nuclear accumulation of an uncapped RNA produced by Drosha cleavage of a transcript encoding miR-10b and HOXD4.

Nuclear accumulation of an uncapped RNA produced by Drosha cleavage of a transcript encoding miR-10b and HOXD4.

Patterning of the animal embryo's antero-posterior (AP) axis is dependent on spatially and temporally regulated Hox gene expression. The murine Hoxd4 gene has been proposed to harbour two promoters, an upstream promoter P2, and a downstream promoter P1, that lie 5.2 and 1.1 kilobase pairs (kb)...

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Bibliographic Details
Main Authors: Sze Lynn Calista Phua, V Sivakamasundari, Yu Shao, Xiaohan Cai, Li-Feng Zhang, Thomas Lufkin, Mark Featherstone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3185001?pdf=render

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http://europepmc.org/articles/PMC3185001?pdf=render

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