Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity

Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity

Fatty acid elongases and desaturases play an important role in hepatic and whole body lipid composition. We examined the role that key transcription factors played in the control of hepatic elongase and desaturase expression. Studies with peroxisome proliferator-activated receptor α (PPARα)-deficien...

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Bibliographic Details
Main Authors: Yun Wang, Daniela Botolin, Jinghua Xu, Barbara Christian, Ernestine Mitchell, Bolleddula Jayaprakasam, Muraleedharan Nair, Jeffery M. Peters, Julia Busik, L. Karl Olson, Donald B. Jump
Format: Article
Language:English
Published: Elsevier 2006-09-01
Series:Journal of Lipid Research
Subjects:
peroxisome proliferator-activated receptor α
sterol-regulatory element binding protein-1
carbohydrate-regulatory element binding protein
MAX-like factor X
liver X receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434704

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http://www.sciencedirect.com/science/article/pii/S0022227520434704

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