The Role of Organic Cation Transporters in the Pharmacokinetics, Pharmacodynamics and Drug–Drug Interactions of Tyrosine Kinase Inhibitors

The Role of Organic Cation Transporters in the Pharmacokinetics, Pharmacodynamics and Drug–Drug Interactions of Tyrosine Kinase Inhibitors

Tyrosine kinase inhibitors (TKIs) decisively contributed in revolutionizing the therapeutic approach to cancer, offering non-invasive, tolerable therapies for a better quality of life. Nonetheless, degree and duration of the response to TKI therapy vary depending on cancer molecular features, the ab...

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Bibliographic Details
Main Authors: Fangrui Xiu, Magdalena Rausch, Zhibo Gai, Shanshan Su, Shijun Wang, Michele Visentin
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
drug–drug interaction
organic cation transporter
pharmacokinetics
SLC
tyrosine kinase
TKI
Online Access:https://www.mdpi.com/1422-0067/24/3/2101

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https://www.mdpi.com/1422-0067/24/3/2101

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