Tilorone and Cridanimod Protect Mice and Show Antiviral Activity in Rats despite Absence of the Interferon-Inducing Effect in Rats

Tilorone and Cridanimod Protect Mice and Show Antiviral Activity in Rats despite Absence of the Interferon-Inducing Effect in Rats

The synthetic compounds, Tilorone and Cridanimod, have the antiviral activity which initially had been ascribed to the capacity to induce interferon. Both drugs induce interferon in mice but not in humans. This study investigates whether these compounds have the antiviral activity in mice and rats s...

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Bibliographic Details
Main Authors: Viktoriya Keyer, Laura Syzdykova, Gulzat Zauatbayeva, Aigerim Zhulikeyeva, Yerlan Ramanculov, Alexandr V. Shustov, Zarina Shulgau
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
Tilorone
Cridanimod
interferon inducing agent
small animal models
Venezuelan equine encephalitis virus
antiviral state
Online Access:https://www.mdpi.com/1424-8247/15/5/617

Internet

https://www.mdpi.com/1424-8247/15/5/617

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