Lrig1 expression identifies quiescent stem cells in the ventricular-subventricular zone from postnatal development to adulthood and limits their persistent hyperproliferation

Abstract Background We previously identified Leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1) as a marker of long-term neurogenic stem cells in the lateral wall of the adult mouse brain. The morphology of the stem cells thus identified differed from the canonical B1 type stem cells, ra...

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Bibliographic Details
Main Authors: Hyung-song Nam, Mario R. Capecchi
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Neural Development
Subjects:
Online Access:https://doi.org/10.1186/s13064-022-00169-1