Evaluation of mesalazine polymeric conjugate in the treatment of actinic proctitis in rats

Evaluation of mesalazine polymeric conjugate in the treatment of actinic proctitis in rats

ABSTRACT Purpose: The present study aimed at testing a new formulation of mesalazine linked to chondroitin sulfate and its components alone in the treatment of actinic proctitis in rats. Methods: Forty-seven female Wistar rats were submitted to pelvic radiation and divided into eight groups: contr...

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Bibliographic Details
Main Authors: Vinícius Rodrigues Taranto Nunes, Paula Vieira Teixeira Vidigal, Márcio Tadeu Pereira, Luís Carlos Duarte Ladeira, Marcelo Vidigal Caliari, Fabrício Marcus Silva Oliveira, Aina Liz Alves Cesar, André Augusto Gomes Faraco, Rafael Calvão Barbuto, Ivana Duval-Araujo
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021-10-01
Series:Acta Cirúrgica Brasileira
Subjects:
Radiotherapy
Proctitis
Mesalamine
Chondroitin
Inflammation
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000800205&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000800205&tlng=en

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