Effects of Andrographolide on Intracellular pH Regulation, Cellular Migration, and Apoptosis in Human Cervical Cancer Cells (Running Tittle: Effects of Andrographolide on pH Regulators and Apoptosis in Cervical Cancer)

Effects of Andrographolide on Intracellular pH Regulation, Cellular Migration, and Apoptosis in Human Cervical Cancer Cells (Running Tittle: Effects of Andrographolide on pH Regulators and Apoptosis in Cervical Cancer)

Cancer cells have been characterized with alkaline intracellular pH (pH<sub>i</sub>) values (&#8805;7.2) to enable cancer proliferation, migration, and progression. The aim of the present study was to explore the concentration-dependent effects of Andrographolide, an active diterpeno...

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Bibliographic Details
Main Authors: Shih-Hurng Loh, Yi-Ting Tsai, Shu-Fu Huang, Tien-Chieh Yu, Pei-Chun Kuo, Shih-Chi Chao, Mei-Fang Chou, Chien-Sung Tsai, Shiao-Pieng Lee
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
andrographolide
intracellular ph
na<sup>+</sup>/h<sup>+</sup> exchanger isoform 1
human cervical cancer cells
migration
apoptosis
pro-caspase-3
bcl-2
parp
Online Access:https://www.mdpi.com/2072-6694/12/2/387

Internet

https://www.mdpi.com/2072-6694/12/2/387

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