PDTC ameliorates neuropathic pain by inhibiting microglial activation <em>via</em> blockage of the TNFα-CX3CR1 pathway

Previous studies have suggested that pyrrolidine dithiocarbamate (PDTC), a nuclear factor κB (NF-κB) inhibitor, play a role in deterring nerve injury-induced neuropathic pain (NP) The activation of NF-κB pathway may contribute to spinal microglial activation, CX3CR1 and tumor necrosis factor-alpha (...

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Bibliographic Details
Main Authors: Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan
Format: Article
Language:English
Published: PAGEPress Publications 2021-03-01
Series:European Journal of Histochemistry
Subjects:
Online Access:https://www.ejh.it/index.php/ejh/article/view/3184