PDTC ameliorates neuropathic pain by inhibiting microglial activation <em>via</em> blockage of the TNFα-CX3CR1 pathway
Previous studies have suggested that pyrrolidine dithiocarbamate (PDTC), a nuclear factor κB (NF-κB) inhibitor, play a role in deterring nerve injury-induced neuropathic pain (NP) The activation of NF-κB pathway may contribute to spinal microglial activation, CX3CR1 and tumor necrosis factor-alpha (...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2021-03-01
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Series: | European Journal of Histochemistry |
Subjects: | |
Online Access: | https://www.ejh.it/index.php/ejh/article/view/3184 |