Biomarkers in Adult-Type Diffuse Gliomas: Elevated Levels of Circulating Vesicular Heat Shock Protein 70 Serve as a Biomarker in Grade 4 Glioblastoma and Increase NK Cell Frequencies in Grade 3 Glioma

Biomarkers in Adult-Type Diffuse Gliomas: Elevated Levels of Circulating Vesicular Heat Shock Protein 70 Serve as a Biomarker in Grade 4 Glioblastoma and Increase NK Cell Frequencies in Grade 3 Glioma

The presence of circulating Hsp70 levels and their influence on the immunophenotype of circulating lymphocyte subsets were examined as diagnostic/prognostic biomarkers for the overall survival (OS) in patients with IDH-mutant WHO grade 3 oligodendroglioma, astrocytoma, and IDH-wildtype grade 4 gliob...

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Bibliographic Details
Main Authors: Philipp Lennartz, Dennis Thölke, Ali Bashiri Dezfouli, Mathias Pilz, Dominik Lobinger, Verena Messner, Hannah Zanth, Karen Ainslie, Morteza Hasanzadeh Kafshgari, Gerhard Rammes, Markus Ballmann, Martin Schlegel, Gemma Ann Foulds, Alan Graham Pockley, Friederike Schmidt-Graf, Gabriele Multhoff
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomedicines
Subjects:
biomarkers
liquid biopsy
extracellular free and vesicular Hsp70
plasma membrane bound Hsp70
glioblastoma
oligodendroglioma
Online Access:https://www.mdpi.com/2227-9059/11/12/3235

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https://www.mdpi.com/2227-9059/11/12/3235

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