Biomarkers in Adult-Type Diffuse Gliomas: Elevated Levels of Circulating Vesicular Heat Shock Protein 70 Serve as a Biomarker in Grade 4 Glioblastoma and Increase NK Cell Frequencies in Grade 3 Glioma
The presence of circulating Hsp70 levels and their influence on the immunophenotype of circulating lymphocyte subsets were examined as diagnostic/prognostic biomarkers for the overall survival (OS) in patients with IDH-mutant WHO grade 3 oligodendroglioma, astrocytoma, and IDH-wildtype grade 4 gliob...
Main Authors: | Philipp Lennartz, Dennis Thölke, Ali Bashiri Dezfouli, Mathias Pilz, Dominik Lobinger, Verena Messner, Hannah Zanth, Karen Ainslie, Morteza Hasanzadeh Kafshgari, Gerhard Rammes, Markus Ballmann, Martin Schlegel, Gemma Ann Foulds, Alan Graham Pockley, Friederike Schmidt-Graf, Gabriele Multhoff |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-12-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/11/12/3235 |
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