Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease
Abstract Background Ultrasound‐determined gallbladder wall thickness is widely used to aid in the diagnosis of gallbladder disease, but no reference values supported by published measurement data are available in dogs. Hypothesis/Objective Establish normal thickness of the gallbladder wall in dogs....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-09-01
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| Series: | Journal of Veterinary Internal Medicine |
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| Online Access: | https://doi.org/10.1111/jvim.16810 |
| _version_ | 1827854456880889856 |
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| author | Carlos Martinez Daniel Davies Séamus Hoey Robert E. Shiel Emma J. O'Neill |
| author_facet | Carlos Martinez Daniel Davies Séamus Hoey Robert E. Shiel Emma J. O'Neill |
| author_sort | Carlos Martinez |
| collection | DOAJ |
| description | Abstract Background Ultrasound‐determined gallbladder wall thickness is widely used to aid in the diagnosis of gallbladder disease, but no reference values supported by published measurement data are available in dogs. Hypothesis/Objective Establish normal thickness of the gallbladder wall in dogs. Animals Fifty‐three dogs presented to a referral hospital and required abdominal ultrasound examination for reasons unrelated to primary hepatobiliary disease. Methods Cross‐sectional observational study recruiting dogs requiring abdominal ultrasound examination. A standard sequence of gallbladder wall images was recorded for later review. Inclusion criteria were normal ultrasonographic hepatobiliary, pancreatic, and small intestinal findings. Exclusion was determined by 2 European College of Veterinary Internal Medicine (ECVIM)‐certified veterinary internists blinded to gallbladder wall thickness data. Dogs were excluded if they had inadequate medical records, a previous history of hepatobiliary, gastrointestinal, or pancreatic disease likely to impact the biliary system (eg, chronic vomiting, nausea, jaundice, diarrhea), unexplained increases in liver enzyme activities, hypoalbuminemia, or ascites. Gallbladder wall thickness was determined by 2 European College of Veterinary Diagnostic Imaging (ECVDI)‐certified veterinary radiologists working together to generate a consensus for each dog. The final output was the maximum normal wall thickness for this population of dogs. Results The upper limit for gallbladder wall thickness in 53 fasted (8 hours) dogs <40 kg was 1.30 mm (90% confidence interval, 1.19‐1.41). Conclusions and Clinical Importance Normal gallbladder wall thickness in dogs is lower than previously reported. Additional studies are required to determine potential effects of body weight and the optimal cut‐off to distinguish between healthy and diseased gallbladders. |
| first_indexed | 2024-03-12T11:23:06Z |
| format | Article |
| id | doaj.art-731ea45e69c5439f9d4cae6c2fb6bf37 |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-03-12T11:23:06Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-731ea45e69c5439f9d4cae6c2fb6bf372023-09-01T14:18:40ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762023-09-013751766177110.1111/jvim.16810Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary diseaseCarlos Martinez0Daniel Davies1Séamus Hoey2Robert E. Shiel3Emma J. O'Neill4Department of Internal Medicine AÚNA Especialidades Veterinarias ‐ IVC Evidensia Valencia SpainHighcroft Referrals Bristol UKSchool of Veterinary Medicine University College Dublin, Belfield Co. Dublin IrelandSchool of Veterinary Medicine Murdoch University Perth Western Australia AustraliaSchool of Veterinary Medicine University College Dublin, Belfield Co. Dublin IrelandAbstract Background Ultrasound‐determined gallbladder wall thickness is widely used to aid in the diagnosis of gallbladder disease, but no reference values supported by published measurement data are available in dogs. Hypothesis/Objective Establish normal thickness of the gallbladder wall in dogs. Animals Fifty‐three dogs presented to a referral hospital and required abdominal ultrasound examination for reasons unrelated to primary hepatobiliary disease. Methods Cross‐sectional observational study recruiting dogs requiring abdominal ultrasound examination. A standard sequence of gallbladder wall images was recorded for later review. Inclusion criteria were normal ultrasonographic hepatobiliary, pancreatic, and small intestinal findings. Exclusion was determined by 2 European College of Veterinary Internal Medicine (ECVIM)‐certified veterinary internists blinded to gallbladder wall thickness data. Dogs were excluded if they had inadequate medical records, a previous history of hepatobiliary, gastrointestinal, or pancreatic disease likely to impact the biliary system (eg, chronic vomiting, nausea, jaundice, diarrhea), unexplained increases in liver enzyme activities, hypoalbuminemia, or ascites. Gallbladder wall thickness was determined by 2 European College of Veterinary Diagnostic Imaging (ECVDI)‐certified veterinary radiologists working together to generate a consensus for each dog. The final output was the maximum normal wall thickness for this population of dogs. Results The upper limit for gallbladder wall thickness in 53 fasted (8 hours) dogs <40 kg was 1.30 mm (90% confidence interval, 1.19‐1.41). Conclusions and Clinical Importance Normal gallbladder wall thickness in dogs is lower than previously reported. Additional studies are required to determine potential effects of body weight and the optimal cut‐off to distinguish between healthy and diseased gallbladders.https://doi.org/10.1111/jvim.16810canineimagingreference intervalultrasonography |
| spellingShingle | Carlos Martinez Daniel Davies Séamus Hoey Robert E. Shiel Emma J. O'Neill Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease Journal of Veterinary Internal Medicine canine imaging reference interval ultrasonography |
| title | Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease |
| title_full | Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease |
| title_fullStr | Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease |
| title_full_unstemmed | Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease |
| title_short | Ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease |
| title_sort | ultrasonographic measurement of gallbladder wall thickness in fasted dogs without signs of hepatobiliary disease |
| topic | canine imaging reference interval ultrasonography |
| url | https://doi.org/10.1111/jvim.16810 |
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