Circular RNA CircCOL5A1 Sponges the MiR-7-5p/Epac1 Axis to Promote the Progression of Keloids Through Regulating PI3K/Akt Signaling Pathway

Circular RNA CircCOL5A1 Sponges the MiR-7-5p/Epac1 Axis to Promote the Progression of Keloids Through Regulating PI3K/Akt Signaling Pathway

Keloids, as a result of abnormal wound healing in susceptible individuals, are characterized by the hyper-proliferation of fibroblasts and exaggerated deposition of extracellular matrix. Current surgical and therapeutic modalities provide limited satisfactory results. Growing evidence has highlighte...

Full description

Bibliographic Details
Main Authors: Wenchang Lv, Shengxuan Liu, Qi Zhang, Weijie Hu, Yiping Wu, Yuping Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
keloid
fibroblast
circCOL5A1
miR-7-5p
Epac1
PI3K/Akt pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.626027/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.626027/full

Similar Items