Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution

<p>Abstract</p> <p>Background</p> <p>Cationic antimicrobial peptides (CAMPs) are well recognized to be promising as novel antimicrobial and antitumor agents. To obtain novel skeletons of CAMPs, we propose a simple strategy using acid-amide substitution (i.e. Glu→Gln, As...

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Bibliographic Details
Main Authors: Tamada Yasushi, Taichi Misako, Nishiuchi Yuji, Minaba Masaomi, Ueno Satoshi, Yamazaki Toshimasa, Kato Yusuke
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Annals of Clinical Microbiology and Antimicrobials
Online Access:http://www.ann-clinmicrob.com/content/10/1/11