TRPM2-mediated Ca2+ signaling as a potential therapeutic target in cancer treatment: an updated review of its role in survival and proliferation of cancer cells
Abstract The transient receptor potential melastatin subfamily member 2 (TRPM2), a thermo and reactive oxygen species (ROS) sensitive Ca2+-permeable cation channel has a vital role in surviving the cell as well as defending the adaptability of various cell groups during and after oxidative stress. I...
Main Authors: | Eunus S. Ali, Brototi Chakrabarty, Sarker Ramproshad, Banani Mondal, Neloy Kundu, Chandan Sarkar, Javad Sharifi-Rad, Daniela Calina, William C. Cho |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-06-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12964-023-01149-6 |
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