Intronic parent-of-origin dependent differential methylation at the Actn1 gene is conserved in rodents but is not associated with imprinted expression.

Parent-of-origin differential DNA methylation has been associated with regulation of the preferential expression of paternal or maternal alleles of imprinted genes. Based on this association, recent studies have searched for parent-of-origin dependent differentially methylated regions in order to id...

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Bibliographic Details
Main Authors: John D Calaway, José Ignacio Domínguez, Megan E Hanson, Ezequiel C Cambranis, Fernando Pardo-Manuel de Villena, Elena de la Casa-Esperon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3493592?pdf=render