Synthesis, Characterization, and Preliminary In Vitro Cytotoxic Evaluation of a Series of 2-Substituted Benzo [<i>d</i>] [1,3] Azoles

Synthesis, Characterization, and Preliminary In Vitro Cytotoxic Evaluation of a Series of 2-Substituted Benzo [<i>d</i>] [1,3] Azoles

A series of benzo [<i>d</i>] [1,3] azoles 2-substituted with benzyl- and allyl-sulfanyl groups were synthesized, and their cytotoxic activities were in vitro evaluated against a panel of six human cancer cell lines. The results showed that compounds BTA-1 and BMZ-2 have the best inhibito...

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Bibliographic Details
Main Authors: Ozvaldo Linares-Anaya, Alcives Avila-Sorrosa, Francisco Díaz-Cedillo, Luis Ángel Gil-Ruiz, José Correa-Basurto, Domingo Salazar-Mendoza, Adrian L. Orjuela, Jorge Alí-Torres, María Teresa Ramírez-Apan, David Morales-Morales
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
2-substituted benzo [<i>d</i>] [1,3] azoles
in vitro cytotoxicity
breast cancer
ERα and GPER
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/9/2780

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https://www.mdpi.com/1420-3049/26/9/2780

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