Use of Mass Spectrometry to Screen Glycan Early Markers in Hepatocellular Carcinoma

Association between altered glycosylation patterns and poor prognosis in cancer points glycans as potential specific tumor markers. Most proteins are glycosylated and functionally arranged on cell surface and extracellular matrix, mediating interactions and cellular signaling. Thereby, aberrant glyc...

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Bibliographic Details
Main Authors: Raphaela Menezes de Oliveira, Carlos Andre Ornelas Ricart, Aline Maria Araujo Martins
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00328/full