Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury

Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury

Abstract Background Macrophage polarization and reprogramming in the lung play a critical role in the initiation, development and progression of acute lung injury (ALI). Regulating the activation and differentiation of pulmonary macrophages may provide a potential therapeutic strategy to treat ALI....

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Bibliographic Details
Main Authors: Lu Wang, Huasheng Zhang, Liya Sun, Wei Gao, Ye Xiong, Aying Ma, Xiali Liu, Lei Shen, Qiang Li, Hong Yang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Nanobiotechnology
Subjects:
Peptide
Gold nanoparticle
Inflammation
Macrophage polarization
Alveolar macrophage
Acute lung injury
Online Access:http://link.springer.com/article/10.1186/s12951-020-00593-7

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http://link.springer.com/article/10.1186/s12951-020-00593-7

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