Recovering mixtures of fast-diffusing states from short single-particle trajectories

Single-particle tracking (SPT) directly measures the dynamics of proteins in living cells and is a powerful tool to dissect molecular mechanisms of cellular regulation. Interpretation of SPT with fast-diffusing proteins in mammalian cells, however, is complicated by technical limitations imposed by...

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Bibliographic Details
Main Authors: Alec Heckert, Liza Dahal, Robert Tjian, Xavier Darzacq
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/70169