Mitophagy protects against silver nanoparticle–induced hepatotoxicity by inhibiting mitochondrial ROS and the NLRP3 inflammasome

Mitophagy protects against silver nanoparticle–induced hepatotoxicity by inhibiting mitochondrial ROS and the NLRP3 inflammasome

Silver nanoparticles (AgNPs) have wide clinical applications because of their excellent antibacterial properties; however, they can cause liver inflammation in animals. Macrophages are among the main cells mediating inflammation and are also responsible for the phagocytosis of nanomaterials. The NLR...

Full description

Bibliographic Details
Main Authors: Jiangyan Li, Ming Li, Ruirui Wang, Jiaqi Lan, Lian Yu, Jie Gao, Hezuo Lü, Qiang Fang, Fengchao Wang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Silver nanoparticles
NLRP3 inflammasome
Mitophagy
Mitochondrial reactive oxygen species
Pyroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324002124

Internet

http://www.sciencedirect.com/science/article/pii/S0147651324002124

Similar Items