Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes

Abstract To obtain a comprehensive picture of composite genetic driver events and clonal dynamics in subtypes of paediatric acute lymphoblastic leukaemia (ALL) we analysed tumour-normal whole genome sequencing and expression data from 361 newly diagnosed patients. We report the identification of bot...

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Bibliographic Details
Main Authors: James B. Studd, Alex J. Cornish, Phuc H. Hoang, Philip Law, Ben Kinnersley, Richard Houlston
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-021-00570-9