Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes
Abstract To obtain a comprehensive picture of composite genetic driver events and clonal dynamics in subtypes of paediatric acute lymphoblastic leukaemia (ALL) we analysed tumour-normal whole genome sequencing and expression data from 361 newly diagnosed patients. We report the identification of bot...
Main Authors: | James B. Studd, Alex J. Cornish, Phuc H. Hoang, Philip Law, Ben Kinnersley, Richard Houlston |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-11-01
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Series: | Blood Cancer Journal |
Online Access: | https://doi.org/10.1038/s41408-021-00570-9 |
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