Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia.

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia.

The role of host genetic variation in the development of complicated Staphylococcus aureus bacteremia (SAB) is poorly understood. We used whole exome sequencing (WES) to examine the cumulative effect of coding variants in each gene on risk of complicated SAB in a discovery sample of 168 SAB cases (8...

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Main Authors: William K Scott, Felix Mba Medie, Felicia Ruffin, Batu K Sharma-Kuinkel, Derek D Cyr, Shengru Guo, Derek M Dykxhoorn, Robert L Skov, Niels E Bruun, Anders Dahl, Christian J Lerche, Andreas Petersen, Anders Rhod Larsen, Trine Kiilerich Lauridsen, Helle Krogh Johansen, Henrik Ullum, Erik Sørensen, Christian Hassager, Henning Bundgaard, Henrik C Schønheyder, Christian Torp-Pedersen, Louise Bruun Østergaard, Magnus Arpi, Flemming Rosenvinge, Lise T Erikstrup, Mahtab Chehri, Peter Søgaard, Paal S Andersen, Vance G Fowler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6192642?pdf=render

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http://europepmc.org/articles/PMC6192642?pdf=render

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