Evaluating the performance of tools used to call minority variants from whole genome short-read data [version 2; referees: 2 approved]

Background: High-throughput whole genome sequencing facilitates investigation of minority virus sub-populations from virus positive samples. Minority variants are useful in understanding within and between host diversity, population dynamics and can potentially assist in elucidating person-person tr...

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Bibliographic Details
Main Authors: Khadija Said Mohammed, Nelson Kibinge, Pjotr Prins, Charles N. Agoti, Matthew Cotten, D.J. Nokes, Samuel Brand, George Githinji
Format: Article
Language:English
Published: Wellcome 2018-09-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-21/v2